Agenda

• Welcome by the host
• Welcome by the Chairman, Jaroslav Slobodnik
• Round table of participants
• Approval of the agenda

Pitch presentations, 10 min per WG + 5 min questions on the essential points: achievements and future plans (extensive time will be devoted in the World Café of day 2 for discussion of the WG projects)

WG1 Prioritisation (Valeria Dulio, INERIS; Nikiforos Alygizakis, EI; Peter von der Ohe, UBA)

WG2 Bioassays (Henner Hollert, Goethe University of Frankfurt)

WG3 Effect Directed Analysis for identification of hazardous contaminants (Melis Mus-Massei, UFZ; Frederic Béen, VU)

WG4 Nano-and micro scale particulate contaminants (Ralf Kägi, Eawag; Bert van Bavel, NIVA)

WG5 Water reuse and policy support (Geneviève Deviller, DERAC; Lian Lundy, LTU)

WG6: Emerging substances in the indoor environment (Lisa Melymuk, RECETOX, Pim Leonards, VU; Adrian Covaci, Antwerp University)

WG8 CEC in the Marine environment (Fiona Regan, DCU; Brendan McHugh, Marine Institute)

PS-CWG: Cross-Working Group Activity Passive Sampling (Ian Allan, NIVA; Cécile Miège, INRAE)

NTS-CWG: Cross-Working Group Activity Non-target screening (Juliane Hollender, Eawag)

Key messages from the NORMAN Database Workshop (26-27 Oct, Athens) (Jaroslav Slobodnik, EI)

• ToxAI: a holistic risk characterisation and environmental fate prediction tool using deep learning models (Peter von der Ohe, UBA and Reza Aalizadeh, University of Athens)
• Predicting toxicity fingerprints of structures and unidentified NTS-HRMS features via MLinvitroTox trained on hundreds of high throughput in vitro toxicity endpoints from ToxCast/Tox21 (Kasia Arturi, Eawag) 
• Applying Machine Learning to derive Species Sensitivity Distributions and address data gaps in chemical risk assessment (Jordi Minnema, RIVM)

Discussion

• One Health and Early Warning – how does NORMAN contribute?
• How to ensure long-term sustainability and resilience of the NDS
• Substance- and environmental status indicators to measure progress toward zero pollution targets
• Integration of environmental and human monitoring: the role of NORMAN
• Occurrence of chemicals in society (chemicals in articles and waste streams): a new 'environmental' compartment in the scope of NORMAN?
• Latest generation toxicity prediction models for chemicals and unknown structures 

Participants are free to visit the different corners to exchange ideas on the proposed topics. The outcomes will provide precious input for the finalization of the NORMAN JPA 2024 and beyond

• Voting of the Financial and Activity report 2022
• Reporting to GA on financial issues 2022 (Treasurer, Gunnar Thorsen, IVL)
• Election of the Steering Committee (mandate 2024 – 2026)

Workshop on “AI for environmental monitoring and assessment of chemicals and their mixtures” (Jan Koschorreck, UBA)

NORMAN and Joint Danube Survey 5 (Jaroslav Slobodnik, EI)

TerraChem: From soils to apex species: chemical pathways, effects and impacts on terrestrial biodiversity and ecosystem services and applications for better chemicals management (Jaroslav Slobodnik, EI)

Assessing the spectral quality and diagnostic information of MS2 data acquired with LC-ESI-HRMS (Frederic Béen, VU)

Integration of computational toxicity driver prioritization tools to support non-target screening workflows in high-throughput effect-directed analysis (Melis Muz-Massei, UFZ)

Microplastic spiked soda tablets and sandwich filters as promising approaches for round robin testing (Ralf Kägi, Eawag)

Exchange ideas among Working Groups: people will be free to circulate from one discussion corner to the other; discussion with the “visitors” will stimulate new ideas and proposals for cross-linking activities between the WGs.

Discussion